(NOTE: to request these services you can contact your airline, call ahead, or see the nearest information counter or concierge).
Perks: Dozens of shops, dozens of dining options, various services throughout the airport, less than an hour to Chicago, and a variety of transportation options to/from the airport. The airports designs/modifications and staff member training are centered around the Americans with Disabilities Act (ADA) requirements for accessibility (Details here: https://www.ada.gov/2010ADAstandards_index.htm).
Challenges: [Minimal] This airport can take some time to navigate due to its layout. Language barriers are very minimal, with multi-language written information and multilingual staff members (the official website supports dozens of languages besides English).
Access to/from Airport: Approximately 36-minutes by car or 47-minutes train from Downtown Chicago with easy access to Train, Taxi, Limousine, Local Shuttles, Car rental, and Buses (Note: Wheelchair accessible van-style Taxi/Car rental with lift may be limited and may not be available without request).
Maps: https://www.flychicago.com/ohare/map/Pages/printablemaps.aspx In this link, provided by Chicago O’Hare International Airport official website, you’ll find maps of the Facilities (in English), including a very detailed PDF files (that contains the majority of the Accessibility options listed in the section above, the print is small so you may wish to save it to a tablet/device with a zoom-in functionality if you cannot print them large enough). Even with a map in hand, new places can get you turned around, so if this happens, ask the staff for help to get you on your way.